Link to SME partners:
AlbaJuna Therapeutic SL
Leaf Expression Systems Ltd
Link to Academic and Public
research organization partners:
Hospital Medical School
The University of Rouen
John Innes Centre
University of the Arts London
VTT Technical Research Centre of Finland
The University of Rouen Normandiewww.rouenuniversity.univ-rouen.fr
The University of Rouen Normandie (URN) is a comprehensive university welcoming more than 29,000 students in 175 diplomas from Bachelor to PhD. The University counts 2,900 foreign students, almost 2,300 doctoral students, and more than 2,000 staff, including 1,200 faculty members who work within 40 research units. The University of Rouen Normandie is active in a wide range of research areas, which provides the foundation for our interdisciplinary activity. Our strengths range across the science and technology, medicine, social sciences and humanities. Our research covers fields as diverse as materials physics, chemistry, biomedical research, environmental science, international law and education.
The Glyco-MEV laboratory (Glycobiology and Plant Extracellular matrix, http://glycomev.univ-rouen.fr/Home.html) is a research unit of the University of Rouen Normandie. Its overall research activity is dedicated to plant glycobiology, aiming to understand the biosynthesis, structures and functions of oligo- and polysaccharides in plant and microalgae. The research activities are divided into 3 themes, one being focused on the characterization of the glycosylation pathway in plants and microalgae. Therefore, through this topic, the Glyco-MEV group has gained an established position in therapeutic glycoprotein production including monoclonal antibodies, optimization and characterization using plants and microalgae as expression systems. They own a strong IP position with several patents regarding humanization of N-glycosylation of recombinant proteins produced in transgenic plants and two patents related to the production of glycosylated proteins in the diatom P. tricornutum (WO/2012/013337; WO/2009/101160; CA2715107; US8728761). They have identified the protein N-glycosylation pathway in P. tricornutum and have developed extensive knowledge and tools for glycosylation engineering and detailed characterization. This research unit is a part of the Tremplin Carnot I2C which foster the collaboration between academia and industrial partners.
Muriel Bardor, PhD